Clinical trials

Does breathing mild bouts of low oxygen improve walking recovery in persons with spinal injury?

This study investigates the effects of low oxygen therapy on motor recovery. Data we collect will be used to determine if this therapy may increase voluntary movement in persons spinal cord injury.


To participate, you must have sustained a spinal cord injury less than 12 months ago.


You may be asked to provide saliva samples during your visits.

You will be compensated for each visit and in some cases for travel and lodging.

Study duration: 15 visits, 1 year

Visit outline:

  • Screening (1 hour): Initial screening assessment by licensed physical therapist

  • Study Intervention (10 visits, 2-3 hours each): Experimental breathing sessions with training and testing of leg movement and walking ability in response to the breathing intervention, in some cases followed by skilled walking practice over the course of 2 weeks

  • Follow-up (4 visits, 1 hour each): Assessment by a licensed physical therapist researcher, 1 week, 1 month, 6 month, and 1 year post-intervention